Clinical LLM Tools

LLMs, datasets, and frameworks specifically designed for clinical applications including medical text analysis, patient documentation, diagnosis support, and healthcare decision-making. Does NOT include general medical AI, radiology-specific tools, or clinical decision rule development without LLM components.

There are 59 clinical llm tools tracked. The highest-rated is Sam-Osian/PFD-toolkit at 49/100 with 3 stars and 30 monthly downloads.

Get all 59 projects as JSON

curl "https://pt-edge.onrender.com/api/v1/datasets/quality?domain=llm-tools&subcategory=clinical-llm-tools&limit=20"

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#	Tool	Score	Tier	Stars	Language
1	Sam-Osian/PFD-toolkit Analyse Prevention of Future Death (PFD) reports with AI	49	Emerging	3	Python
2	SmartFlowAI/EmoLLM 心理健康大模型 (LLM x Mental Health), Pre & Post-training & Dataset & Evaluation &...	42	Emerging	1,701	Python
3	AI-in-Health/MedLLMsPracticalGuide [Nature Reviews Bioengineering🔥] Application of Large Language Models in...	40	Emerging	1,991	—
4	ELM-Research/ELM A Training and Evaluation Framework for ECG-Language Models (ELMs)	40	Emerging	9	Python
5	mims-harvard/Madrigal Madrigal: Multimodal AI predicts clinical outcomes of drug combinations from...	35	Emerging	40	Jupyter Notebook
6	Zlasejd/HuangDI 黄帝(Huang-Di)模型仓库，基于Ziya-LLaMA-13B-V1的中医古籍知识问答大模型。	35	Emerging	152	Python
7	monarch-initiative/pheval.llm Analysis of LLMs for Clinical Observations	35	Emerging	7	Python
8	X-D-Lab/Sunsimiao 🌿孙思邈中文医疗大模型(Sunsimiao)：提供安全、可靠、普惠的中文医疗大模型	34	Emerging	471	Python
9	kbressem/LongHealth LongHealth: A Question Answering Benchmark with Long Clinical Documents	32	Emerging	28	Python
10	TsinghuaC3I/MedXpertQA [ICML 2025] MedXpertQA: Benchmarking Expert-Level Medical Reasoning and Understanding	32	Emerging	142	Python
11	JhCircle/Kardia-R1 [WWW] Kardia-R1: Unleashing LLMs to Reason toward Understanding and Empathy...	32	Emerging	56	Python
12	yang-ai-lab/HEARTS HEARTS: Benchmarking LLM Reasoning on Health Time Series	31	Emerging	27	Python
13	jqwangai/Medical-LLM A Repository of Medical Large Language Models	30	Emerging	4	—
14	tyang816/Awesome-TCM-LLM Open-source Traditional Chinese Medical Large Language Models. （开源中文医疗大模型合集）	29	Experimental	50	—
15	gersteinlab/MedAgents [ACL 2024 Findings] MedAgents: Large Language Models as Collaborators for...	29	Experimental	330	Python
16	StanfordMIMI/clin-bhc-summ [JAMIA 2024] A dataset and benchmark for hospital course summarization with...	29	Experimental	10	Jupyter Notebook
17	nhsx/ELM4PSIR ELM4PSIR - Exploring Language Modelling for (NHS) Patient Safety Incident...	28	Experimental	6	Jupyter Notebook
18	FreedomIntelligence/Apollo Multilingual Medicine: Model, Dataset, Benchmark, Code	28	Experimental	199	Python
19	alimoezzi/ReportQL Code and dataset for paper - Application of Deep Learning in Generating...	28	Experimental	11	Jupyter Notebook
20	ALSER-Lab/XMorph Official implementation of XMorph: An explainable brain tumor classification...	26	Experimental	4	Jupyter Notebook
21	jcheng5/rmedicine-2025 Slides and examples for R/Medicine workshop "Demystifying LLMs with Ellmer"	25	Experimental	12	R
22	msamprovalaki/Exploring-Multimodal-Large-Language-Models-for-Medical-Image-Captioning This repository includes the code for my Master Thesis, which investigates...	23	Experimental	7	Python
23	Xepond/health-xai-llm Predicting patient health risks with machine learning and using LLMs to...	22	Experimental	—	Jupyter Notebook
24	hossam1522/MedicalExplAIner Using LLMs to predict emergency triage acuity from patient data, evaluated...	22	Experimental	—	Python
25	alif-munim/clinical-camel-asr An end-to-end pipeline for clinical dialogue transcription and summarization...	22	Experimental	3	Python
26	RealPolitiX/qstab Adversarial attacks on biomedical question answering	22	Experimental	1	Python
27	DavePower-cloud/llm-clinical-simulation Multi-agent large language model framework for simulating clinical...	22	Experimental	—	Jupyter Notebook
28	jjfenglab/HACHI Human-AI Co-design for Clinical Prediction Models	22	Experimental	3	Python
29	infosenselab/information-health Large-scale dataset and simulation framework for studying information health.	22	Experimental	—	Jupyter Notebook
30	csinva/clinical-rule-development Building and vetting clinical decision rules.	21	Experimental	10	Jupyter Notebook
31	ammarlodhi255/Chest-xray-report-generation-app-with-chatbot-end-to-end-implementation AI-powered Chest X-ray report generation app using VLM (Swin-T5) and LLM...	21	Experimental	10	Jupyter Notebook
32	albertovalerio/from-segmentation-to-explanation The primary objective of this work is to develop an innovative system...	21	Experimental	2	Jupyter Notebook
33	UKPLab/eacl2026-culturecare Repository for "Tailored Emotional LLM-Supporter: Enhancing Cultural...	20	Experimental	1	JavaScript
34	starmpcc/Asclepius Official Codes for "Publicly Shareable Clinical Large Language Model Built...	19	Experimental	114	Python
35	rhavekost/clinical-toolkit Clinical LLM prompt/skill toolkit for screening, scoring, safety,...	19	Experimental	—	JavaScript
36	cja5553/LLMs_in_perioperative_care Codes for: Alba, C., Xue, B., Abraham, J. et al. The foundational...	18	Experimental	5	Jupyter Notebook
37	balaji1233/AI-Radiology-Reporting Using MAIRA-2 multimodal transformer designed for the generation of...	18	Experimental	2	Jupyter Notebook
38	blabla9111/PINN_LLM Expert-guided forecasting of epidemic ARI incidence based on...	18	Experimental	5	Jupyter Notebook
39	giuseppericcio/MediCARE 📄 Preprint submitted to Artificial Intelligence in Medicine 🏥 - "MediCARE:...	17	Experimental	3	Jupyter Notebook
40	kelkalot/normedqa NorMedQA is designed to evaluate the medical knowledge and reasoning...	17	Experimental	6	Jupyter Notebook
41	BARUDA-AI/Awesome-Medical-LLM Large language model of Medical AI, General Medical AI (GMAI)	16	Experimental	17	—
42	vnleonenko/Epi_PINN_LLM Expert-Guided PINN is a system for interactive epidemiological forecasting...	15	Experimental	5	Jupyter Notebook
43	cghr-toronto/wen-et-al-2025-cava Computer Assisted Verbal Autopsy: Comparing Large Language Models to...	14	Experimental	—	BibTeX Style
44	Mattjesc/RtDC-LLM-IoT-Health Real-time Data Capture for Integration with LLMs to Enhance User Experience...	14	Experimental	1	CSS
45	grauso-t/Medical-AI Tesi di laurea triennale. Utilizzo dei Large Language Models (LLM) per...	14	Experimental	—	Python
46	ParthaPRay/diverticulitis_ollama_LLM This repo presents codes that helps patients to get informed about...	13	Experimental	—	Python
47	GaoxiangLuo/LLM-BioMed-NER-RE [npj Digital Medicine] An In-Depth Evaluation of Federated Learning on...	13	Experimental	11	Jupyter Notebook
48	AlexanderSychev2005/radio-analysis This repository contains an R&D project focused on the automated...	13	Experimental	2	Python
49	ganeshvannam/tinyllama-clinical-assistant- This is my final project in Artificial Intelligence in Health Care course	12	Experimental	1	Jupyter Notebook
50	openlifescience-ai/Awesome-AI-LLMs-in-Radiology A curated list of awesome resources, papers, datasets, and tools related to...	12	Experimental	43	—
51	finnschwall/RIXA User centered XAI - made easy	12	Experimental	1	CSS
52	marswen/ThreeSensei Leverage LLM agent to conduct clinical consultation	12	Experimental	3	Python
53	McJackTang/LLM-HealthAssistant ALPHA: AnomaLous Physiological Health Assessment Using Large Language Models...	12	Experimental	19	Jupyter Notebook
54	eejji/CIEDep-Net Depression detection using audio, text and LLMs	11	Experimental	—	—
55	windisch-paul/positive_negative Data and code associated with the manuscript "Large Language Models for...	11	Experimental	—	Jupyter Notebook
56	yuan-phd/decisionlens DecisionLENS — A clinical trial decision support platform built on 573,674...	11	Experimental	—	Jupyter Notebook
57	criticalml-uw/EvalPrompt Analyzing medical misinformation when using LLMs for self-diagnosis.	10	Experimental	1	Jupyter Notebook
58	giuseppericcio/Awesome-NER-for-Healthcare A collection of resources that showcase the applications of NER in Healthcare domain.	10	Experimental	1	—
59	junayed-hasan/LLM-Aggregated-Ensemble-Clinical-Outcomes Implementation of a novel method using aggregated ensembles of large...	10	Experimental	1	Jupyter Notebook