Multi-Agent Orchestration ML Frameworks

Frameworks and platforms for coordinating multiple AI agents, LLMs, and services to work together on complex tasks. Does NOT include single-agent chatbots, deployment management tools, or workforce simulation without agent coordination focus.

There are 67 multi-agent orchestration frameworks tracked. 1 score above 70 (verified tier). The highest-rated is microsoft/SynapseML at 72/100 with 5,211 stars. 1 of the top 10 are actively maintained.

Get all 67 projects as JSON

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# Framework Score Tier
1 microsoft/SynapseML

Simple and Distributed Machine Learning

72
Verified
2 codeintegrity-ai/mutahunter

Open Source, Language Agnostic Mutation Testing

49
Emerging
3 elevenlabs/elevenlabs-android

Official ElevenLabs Kotlin SDK

41
Emerging
4 MilesONerd/neurenix

Empowering Intelligent Futures, One Edge at a Time.

37
Emerging
5 jmanhype/ace-playbook

Self-improving LLM system using Generator-Reflector-Curator pattern for...

37
Emerging
6 cortictechnology/cep

CEP is a software platform designed for users that want to learn or rapidly...

36
Emerging
7 evilsocket/ergo

🧠 A tool that makes AI easier.

36
Emerging
8 maikherbig/AIDeveloper

GUI-based software for training, evaluating and applying deep neural nets...

36
Emerging
9 AICU-HEALTH/aicuflow-python

(Working Beta) Integrate data collection, machine learning and big data...

34
Emerging
10 incocreativedev/tessera-core

An activation-based protocol for AI-to-AI knowledge transfer across architectures

34
Emerging
11 1m1-github/LoopOS.jl

Digital Consciousness

34
Emerging
12 pigeonposse/brainvat

This artificial intelligence library is designed to provide a more human and...

33
Emerging
13 noduslabs/eightos

Bodymind Operating System

32
Emerging
14 ceoweggo/Corebrain

Corebrain is an SDK-based solution that allows developers to integrate...

31
Emerging
15 HabanaAI/SynapseAI_Core

SynapseAI Core is a reference implementation of the SynapseAI API running on...

31
Emerging
16 CMBAgents/synapses

Multi-domain AI assistant for exploring top Python libraries

30
Emerging
17 DarthMetaCrypro/Aeonmi

Aeonmi is a next-generation programming language designed for AI-native...

30
Emerging
18 yashab-cyber/neo

The Next-Generation AI Assistant for Complete Digital Transformation NEO...

29
Experimental
19 Divyarajsinh-Dodia/LocatAI.NET

AI Locator Finder

29
Experimental
20 TestOptimal/MBT

TestOptimal MBT (Open-Source)

25
Experimental
21 NeuraXenetica/synaptans-workforcesim

Synaptans WorkforceSim is a free open-source web app for simulating the...

24
Experimental
22 pigeonposse/bravecore

Bravecore is an innovative library that integrates complete emotion and...

23
Experimental
23 arun0102/CircleOfSearch

Android Circle to Search Feature

23
Experimental
24 Gxz111/mnemosyne

Provides a cognitive memory system for AI agents to manage knowledge and...

22
Experimental
25 damienos61/SynapSwap

Predictive VRAM Virtualization Engine

22
Experimental
26 Baki233619/le-os

🔄 Rebase your Fedora installation seamlessly with le-os, an experimental...

22
Experimental
27 zev0ss/SynapseCore

⚙️ Enable real-time predictive modeling and scalable data enrichment with...

22
Experimental
28 KeplerSynapseNet/synapsenet-interfaces

SynapseNet Interface Specifications — Core protocol design, Proof of...

22
Experimental
29 quarkiverse/quarkus-semantic-kernel

This extension eases the integration of Semantic Kernel for Java with Quarkus

22
Experimental
30 Samuele95/neos

NEOS — Neural Field Operating System v1.0. A shell-like command interface...

22
Experimental
31 rakluu000/Synapse

🧩 Orchestrate multiple AI models to generate, review, and deliver...

22
Experimental
32 James-028/mhfu_transmog

Change weapon and armor appearance in Monster Hunter Freedom Unite without...

22
Experimental
33 yigit-guven/Synapse-AI

Synapse AI combines local LLMs with vector search to transform your private...

20
Experimental
34 ernakkc/Synapse

AI-powered assistant with intelligent memory system and natural language...

20
Experimental
35 EricLBuehler/The-Neuron

An autonomous robot, powered by AI.

19
Experimental
36 resonantlabsai/synaptic

Local-first AI memory store with synaptic dynamics (strengthen/decay/prune)...

19
Experimental
37 petrol123/SECE

SECE is an open, modular framework for modeling emotion in artificial...

19
Experimental
38 ElliotOne/nl-semantic-kernel-sales-analyzer

A console project showing Microsoft Semantic Kernel examples for sales data...

18
Experimental
39 cesumilo/LoveBrains

LoveBrains is a simulator of artificial intelligence based on a plugin system.

18
Experimental
40 Nemois-git/Prometheus

Prometheus: The AI, Built by AI.

17
Experimental
41 jayspolitz/aicuflow-arduino

🚀 Streamline machine learning with the Aicuflow Arduino library for data...

16
Experimental
42 SyncfusionExamples/Integrating-AI-Driven-Location-Search-into-.NET-MAUI-Maps

This repository contains sample code demonstrating how to integrate...

16
Experimental
43 Kayariyan28/wrappedEther

wrappedEther is a real-time data sculpture that turns invisible flows of...

15
Experimental
44 tanosshi/WinToSearch

Circle To Search for Windows

15
Experimental
45 kyprware/synapse

A network hub for communication between Agents, Applications and LLMs

15
Experimental
46 thennen/Synaptogen

A fast generative model for stochastic memory cells

15
Experimental
47 Adarsh-Aravind/NUEROMESH

NUEROMESH is an AI-based project focused on exploring neural network...

15
Experimental
48 garisonz/synapse-gz

A full-stack ML platform for end-to-end data exploration, feature...

14
Experimental
49 ismo98/trolley

Run and distribute terminal-based apps easily across Linux and MacOS with...

14
Experimental
50 KOSASIH/eonix-network

The network repository for the Eonix project, containing the proof-of-stake...

14
Experimental
51 SirMusk17/aicuflow-android

📱 Stream data effortlessly from your Android device to the Aicuflow platform...

14
Experimental
52 curiosity-ai/codeproject-search

AI-powered search demo on CodeProject's articles

13
Experimental
53 ldilley/frank

:bulb: Fairly Rational Artificial Neural Kludge

13
Experimental
54 lps-js/lps-cli

Logic Production System (LPS) CLI Toolset using lps.js

13
Experimental
55 martinkorelic/semantko

Semantko je napredna slovenska igra konteksta, kjer je cilj odkriti skrivno...

13
Experimental
56 AICU-HEALTH/aicuflow-arduino

The aicuflow client on Arduino-ESP32/8266 and others! Collect sensor data,...

13
Experimental
57 dimitrivlachos/Proto-OS

An operating system for a Protogen head which utilises computer vision and...

12
Experimental
58 raminf/RoboNope-nginx

Take control of your own content. Enforce access to disallowed web URLs.

12
Experimental
59 semack/TxtAI.NET

Semantic search and workflows for .NET

12
Experimental
60 swagfin/AI.TransactionExtracter.API

A lightweight AI-powered .NET API that extracts key transaction entities...

12
Experimental
61 beltromatti/NoesisAI

Noesis AI is a non-profit research organization developing brain-inspired...

12
Experimental
62 Unix69/BrainOS

An innovative and sperimental 64 bit Bare Metal Operative System based on...

11
Experimental
63 jp30566347/synapsia

Synapsia Landing

11
Experimental
64 cartheur/aeon

A machine intelligence (MI) program that is a differentiator of how others...

11
Experimental
65 duongddinh/OS-research-lab

Exploring kernel-level operating system design through simulation and...

11
Experimental
66 Israel-Mafabi-Emmanuel/SynapseVision

A web application utilizing the power of AI in explaining uploaded images...

10
Experimental
67 GeToNIX531/Aurora-Framework

Ломай всё. Нет границ, имея интеллект.

10
Experimental