Multi-Disease Risk Assessment ML Frameworks

Tools for predicting risk across multiple disease types (diabetes, kidney disease, anemia, malaria, hepatitis, etc.) using ML models on patient data. Does NOT include single-disease prediction, cardiac-specific tools, or general health monitoring without clinical risk scoring.

There are 99 multi-disease risk assessment frameworks tracked. 1 score above 50 (established tier). The highest-rated is dssg/triage at 69/100 with 199 stars and 334 monthly downloads.

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#	Framework	Score	Tier	Stars	Language
1	dssg/triage General Purpose Risk Modeling and Prediction Toolkit for Policy and Social...	69	Established	199	Jupyter Notebook
2	shobhitsrivastava-ds/ML-MT-WebApp This project is all about a Machine Learning based Medical Test web app...	43	Emerging	215	HTML
3	kanchitank/Medibuddy-Smart-Disease-Predictor Multiple disease prediction such as Diabetes, Heart disease, Kidney disease,...	38	Emerging	100	Jupyter Notebook
4	anujdutt9/Disease-Prediction-from-Symptoms Disease Prediction based on Symptoms.	36	Emerging	334	Jupyter Notebook
5	advikmaniar/ML-Healthcare-Web-App This is a Machine Learning web app developed using Python and StreamLit....	35	Emerging	45	Python
6	venugopalkadamba/Multi_Disease_Predictor A Machine Learning and Deep Learning based webapp used to predict multiple diseases.	34	Emerging	141	Jupyter Notebook
7	kamilpytlak/heart-condition-checker Application to predict heart disease using logistic regression	32	Emerging	11	Python
8	gauravjain2/heart-failure-prediction A WebApp that predicts the likelihood of occurrence of Death Event due to...	31	Emerging	13	Jupyter Notebook
9	sohammanjrekar/Multiple-Disease-Prediction-Webapp Designed web app employs the Streamlit Python library for frontend design...	31	Emerging	52	Python
10	jumpingchu/Pokemon-Sleep 【Python / Streamlit】Pokemon Sleep 小幫手（寶可夢潛力計算、食譜篩選、寶可夢資訊）	29	Experimental	14	Jupyter Notebook
11	thbuerg/MetabolomicsCommonDiseases ⛑ Code for "Metabolomic profiles predict individual multi-disease outcomes" ⛑	29	Experimental	22	Jupyter Notebook
12	MahmoudNagiubX/Multi-Disease-Detection-System Multi Disease Detection System (MDDS) is an AI-powered web application...	28	Experimental	1	HTML
13	fastdatascience/clinical_trial_risk Clinical Trial Risk Tool for analysing clinical trial protocols using...	28	Experimental	12	Jupyter Notebook
14	Vatshayan/Final-Year-Disease-Prediction-Project Final Year Project Diseases Prediction System through Machine Learning....	27	Experimental	108	Jupyter Notebook
15	Prem07a/Heart-Disease "Coding a Streamlit web app for heart disease prediction using a trained...	27	Experimental	8	Jupyter Notebook
16	akthammomani/AI_powered_heart_disease_risk_assessment_app Build a Web App called AI-Powered Heart Disease Risk Assessment App	26	Experimental	4	Jupyter Notebook
17	ArjunCodess/men2-predictor A machine learning pipeline for predicting Multiple Endocrine Neoplasia type...	25	Experimental	3	Python
18	sjapanjots/Multi-class-classificational-Disease-Prediction-Models- A Streamlit-based web application that predicts Diabetes, Heart Disease, and...	24	Experimental	2	Jupyter Notebook
19	Lavishtyagi45/disease-prediction-using-machine-learning Minor project for disease prediction using machine learning classifiers such...	24	Experimental	3	HTML
20	tayalmanan28/PANACEA A web application based on ML model for prediction of disease based on the...	24	Experimental	4	—
21	Zyzzwlh/Project_4-Multiple-Disease-Prediction 🩺 Predict multiple diseases using advanced machine learning techniques to...	24	Experimental	2	Jupyter Notebook
22	M-F-Tushar/Heart-Disease-Prediction-Web-App Machine learning-powered web app for heart disease risk prediction.	23	Experimental	5	Jupyter Notebook
23	parthsompura/Disease-prediction-using-Machine-Learning Implementation of various machine learning algorithms to predict the disease...	23	Experimental	16	Python
24	skibididanieldds1/Complete-Health-Diagnostic-Hub 🩺 Complete Health Diagnostic Hub – A 🌐 web-based platform using 🤖 machine...	22	Experimental	—	HTML
25	carlmonnaert/Medical-AI A comprehensive hospital simulation system integrating discrete event...	22	Experimental	—	Python
26	thyagarajank/Cattle-disease-prediction-using-Machine-Learning Cattle disease prediction using Machine Learning. This project is used to...	22	Experimental	12	Jupyter Notebook
27	sidroy9/Multiple-Disease-Predictor-ML-Flask-WebApp It's an end-to-end Machine Learning Project. The prediction has been done by...	20	Experimental	11	HTML
28	ANUBprad/Project-SWASTHYA Project SWASTHYA is an AI-driven healthcare platform for early cancer...	20	Experimental	1	Jupyter Notebook
29	prachet283/ML-Project-20-Multiple-Disease-Prediction-System-WebApp A comprehensive machine learning-based web app for predicting multiple...	20	Experimental	8	Jupyter Notebook
30	saikeerthi2810/CodeRed Revolutionary AI-powered anemia detection platform combining browser-based...	19	Experimental	—	TypeScript
31	tasfiatasnim18/clinical-decision-support-system An intelligent and scalable clinical decision support system for automated...	19	Experimental	—	JavaScript
32	cepdnaclk/e18-6sp-Disease-Monitoring-in-dairy-industry Automated Dairy Disease Monitoring using machine learning to predict...	19	Experimental	8	Jupyter Notebook
33	global-ad-snap/heart-disease-risk-analysis ML-based heart disease risk prediction with explainability (SHAP) and Streamlit demo	19	Experimental	—	Jupyter Notebook
34	JENILP07/HealthSense-AI HealthSense-AI is an advanced machine learning-powered healthcare...	19	Experimental	—	TypeScript
35	shiroonigami23-ui/SecureHealthIoT Kaggle-based symptom-to-disease prediction pipeline with Gradio and Hugging...	19	Experimental	9	Python
36	Janviswa/Disease-outbreak-prediction-using-Machine-Learning ML-powered system to predict disease outbreaks like Heart Disease, Diabetes,...	18	Experimental	3	Jupyter Notebook
37	yashrajagawane/multiple-disease-prediction-system AI-powered healthcare web application that predicts the risk of multiple...	18	Experimental	7	Python
38	Projects-Developer/Heart-Diseases-Prediction-Project Final Year Project Heart Disease Prediction Project with all Documents.	18	Experimental	61	Jupyter Notebook
39	jmarihawkins/Disease_Prediction_App The Disease Prediction Project uses AI/ML to predict diseases based on...	17	Experimental	4	Jupyter Notebook
40	HumayunK01/CodeRedProject Foresee is a full-stack AI/ML platform for malaria diagnostics and...	17	Experimental	4	TypeScript
41	BhavyaKansal20/healthy-ai AI-POWERED HEALTH INTELLIGENCE \| Advanced machine learning models trained on...	16	Experimental	2	HTML
42	Pranjal-statistics/Disease_Prediction_Model This project focuses on predicting diseases using various machine learning...	16	Experimental	4	—
43	aman-chhetri/MediCare A machine learning web application built using Streamlit that predicts...	16	Experimental	2	Jupyter Notebook
44	mohamedelsayed177/Heart-Disease-Prediction Heart Disease Prediction Project using Machine Learning. Includes data...	15	Experimental	—	Jupyter Notebook
45	Susreel7/Cardiovascular-Disease-Prediction-System-Using-Ensemble-Machine-Learning A robust heart disease risk assessment tool built with Python and Streamlit....	15	Experimental	—	Jupyter Notebook
46	willow788/gp1-anaemia-detection-model AI-powered anemia detection with classical ML, refined datasets, and...	15	Experimental	—	Jupyter Notebook
47	danielnunesdc/healthcare-diagnosis-ai Production-ready Healthcare Machine Learning demo with real data, metrics,...	15	Experimental	—	—
48	apoorvrajdev/heart-disease-ai Healthcare AI + Machine Learning project that predicts heart disease risk...	15	Experimental	1	Jupyter Notebook
49	jamflix/Heart_Disease_Project ❤️ Predict heart disease risk with an advanced machine learning pipeline,...	15	Experimental	1	Jupyter Notebook
50	raza242k5-sys/AI-Health-Diet-System AI-based Health Recommendation System built with Python, Streamlit, ML, and...	15	Experimental	1	Python
51	adarshsingh6622-source/health_ai_project AI-powered Health Analyzer using Machine Learning and Streamlit. It predicts...	15	Experimental	1	Python
52	Vatshayan/Potato-Disease-Prediction-Project Potato Disease Detection Project using Machine learning with Code, Documents...	15	Experimental	6	—
53	deepakrjain/spamurais-medical-risk-analyzer An AI-powered web app that assesses medical risk in real time through a...	15	Experimental	2	CSS
54	ahmad-albasha/EmergencyX 🚨 AI-Powered Emergency Triage & Cardiac Risk Prediction System — Windows...	14	Experimental	—	C#
55	dhrisit07-cloud/heart-disease-predictor Heart disease risk predictor built with XGBoost, SHAP explainability, and...	14	Experimental	—	Jupyter Notebook
56	Shashwatology/BreatheSync BreathySync is an AI-powered respiratory health platform that uses 6-second...	14	Experimental	—	TypeScript
57	Saket22-CS/ai-health-guardian AI-powered disease prediction and health assistant using Random Forest,...	14	Experimental	—	Python
58	sudhandhu10/MediScan-AI AI-powered multi-disease health risk predictor with LLaMA 3.3 70B doctor,...	14	Experimental	—	Python
59	Thunderous-cauliflower413/DeSSyPHER 🌍 Assess health risks from the human exposome with DeSSyPHER, a repository...	14	Experimental	—	Shell
60	ayomideajadi12-hub/sickle-guard-ai AI-powered sickle cell crisis predictor using Edge Impulse ML + Arduino	14	Experimental	—	C++
61	mazen-amr/Helix-disease-prediction ML system to predict Diabetes, Heart Disease & Kidney Disease using XGBoost	14	Experimental	—	Jupyter Notebook
62	luanamariapinheiro/cardiovascular-risk-ai Sistema de alerta de risco cardiovascular utilizando Machine Learning e Streamlit.	14	Experimental	—	Jupyter Notebook
63	Divyanshusinghrajawat/Athlete-Injury-Risk-Predictor Predicts the probability of an athlete getting injured based on physical and...	14	Experimental	—	Jupyter Notebook
64	Devanik21/Heart_disease_Prediction-APP Cardiac risk prediction Streamlit app — XGBoost/RF on Cleveland dataset...	14	Experimental	—	Jupyter Notebook
65	harshitleads/ml-risk-evaluation-tradeoffs Interpretable ML for heart disease risk prediction. Logistic Regression vs...	14	Experimental	—	Jupyter Notebook
66	codedevrosh/multi_disease_prediction Multi-disease prediction system built with Python, Scikit-learn, and...	14	Experimental	—	Jupyter Notebook
67	gben007/heart-disease-predictor-knn A Streamlit-based heart disease prediction app built with a KNN classifier...	14	Experimental	—	Jupyter Notebook
68	andyombogo/open-health-risk-engine Explainable mental health risk demo using NHANES, Streamlit, and SHAP	14	Experimental	—	Python
69	smuhabdullah/Sugarcane_project_3rd_Milestone Final Year Project (Sugarcane disease detector)	14	Experimental	7	SCSS
70	Monu0506577/triage Manage and automate moderation and email triage for Twitter mentions,...	14	Experimental	—	Shell
71	r0manticwarrior/Cardio-Insight-dashboard Top AI Heart Health Tracker 2026 🩺🧬 – Free Predictive Cardio Risk App &...	14	Experimental	—	—
72	dipenpan/heart-disease-prediction-app Machine Learning web app for heart disease prediction using Streamlit and...	14	Experimental	—	Jupyter Notebook
73	vaibhavv-labs/Heart-Disease-Prediction End-to-end Machine Learning project with live deployment to predict heart...	14	Experimental	—	Python
74	priya011006/Heart-Disease-Risk-Predictor A Streamlit-based machine learning web app that predicts the risk of heart...	14	Experimental	—	Python
75	kamal-01-wjua/EarlyPulse End-to-end ML system for early sepsis detection on 20,317 real ICU stays....	14	Experimental	—	Python
76	dnlC9/heart-disease-risk-prediction-mlp 🫀 Predict heart disease risk using a custom neural network, featuring an...	14	Experimental	—	Python
77	lworachat999/HEARTGUARD-AI-for-your-heart 🫀 Predict heart failure risk with HeartGuard, an AI-powered companion...	14	Experimental	—	Python
78	Panda-dotcom-code/PreCare-AI AI-powered preventive healthcare risk prediction system.	14	Experimental	—	Python
79	gben007/disease-risk-predictor treamlit app for predicting disease risk from health and lifestyle data...	14	Experimental	—	Python
80	AhmedHassanGondal/Diagnosis-Modeling Patient flow and diagnosis modeling using Markov chains, HMMs, Bayesian...	14	Experimental	—	Python
81	kushalareddy2006-ar/smart_health_monitoring AI-powered Smart Health Monitoring System using Ensemble Learning...	14	Experimental	—	Python
82	samibahig/HealthMov AI health risk prediction — Cardiovascular & Diabetes models \| HealthMov...	14	Experimental	—	—
83	ishubtripathi/HeartCure HeartCureAI is an AI-powered web application that predicts heart stroke risk...	14	Experimental	—	HTML
84	sayeedjoy/MultiDx A full-stack ML-powered web application for early risk prediction of Ovarian...	13	Experimental	—	TypeScript
85	Akshint0407/Disease-Prediction-App This project is a Streamlit-based web application designed to predict the...	13	Experimental	6	Python
86	malc3om/Health_Gen-Ai AI-powered preventive health platform that predicts heart disease risk 3...	12	Experimental	1	TypeScript
87	AnkushOff/Covid-19-Risk-Predictor A machine learning-based web app that predicts a person's risk level for...	12	Experimental	1	TypeScript
88	deoprakash/multi_disease_prediction A unified Flask web application integrating multiple machine learning and...	12	Experimental	1	HTML
89	gokulraktate/Heart-Disease-Prediction 🩺 A Streamlit web app that predicts heart disease risk using a machine...	11	Experimental	—	Jupyter Notebook
90	Deepu8405/SmartCare-AI---Cardiovascular-Risk-Intelligence A production-grade healthcare platform that combines a dual-model ensemble...	11	Experimental	—	HTML
91	Piyush851/pharmaguard-rift2026 A full-stack precision medicine platform that prevents adverse drug...	11	Experimental	—	JavaScript
92	hirok121/HepatoCAI HepatoCAI - AI-Powered Hepatitis C Diagnosis Platform	11	Experimental	—	JavaScript
93	Atik1219/Anylogic-with-ML-AI An Artificial Neural Network (ANN) model trained using a Microsoft dataset...	11	Experimental	6	—
94	2000pawan/Heart-Dieases-Prediction "Excited to announce my latest project on LinkedIn! ❤️ Introducing my heart...	11	Experimental	2	Jupyter Notebook
95	AshishRathodDev/Aarogya-AI AI-powered medical report analysis platform with fraud detection. FastAPI +...	11	Experimental	—	Jupyter Notebook
96	metacore-stack/DiagnosticAI-Suite Enterprise-grade AI healthcare platform combining machine learning and deep...	11	Experimental	—	HTML
97	geeky-auro/MediGuardian A Capstone Project designed to identify, analyze, and protect sensitive data...	10	Experimental	1	Jupyter Notebook
98	The-Semicolons/Application-of-Boosted-Tree-Classifier-for-Predicting-Disease-from-Symptoms Research based testing of Boosted Tree Classifier for Predicting Disease...	10	Experimental	1	Python
99	bahadirkesgin/civan_ai An AI-powered software solution for predicting COVID-19 test results and...	10	Experimental	1	C#

Comparisons in this category

Medibuddy-Smart-Disease-Predictor and Multi_Disease_Predictor (38 vs 34) Multi_Disease_Predictor and Multiple-Disease-Prediction-Webapp (34 vs 31) Multiple-Disease-Prediction-Webapp and Heart-Disease (31 vs 27) Multiple-Disease-Prediction-Webapp and Multi-class-classificational-Disease-Prediction-Models- (31 vs 24) ML-Healthcare-Web-App and Heart-Disease (35 vs 27) ML-Healthcare-Web-App and AI_powered_heart_disease_risk_assessment_app (35 vs 26) heart-condition-checker and Heart-Disease (32 vs 27)