izgys/antibody-affinity-engineering
A computational pipeline for improving antibody-antigen binding affinity through CDR-focused mutations, using AI-based inverse folding (ProteinMPNN), structural modeling (IgFold, AlphaFold-Multimer), and binding affinity prediction with FoldX. Designed for antibody engineering and rational biologic design.
No commits in the last 6 months.
Stars
2
Forks
—
Language
—
License
—
Category
Last pushed
Jul 05, 2025
Commits (30d)
0
Get this data via API
curl "https://pt-edge.onrender.com/api/v1/quality/ml-frameworks/izgys/antibody-affinity-engineering"
Open to everyone — 100 requests/day, no key needed. Get a free key for 1,000/day.
Higher-rated alternatives
Graylab/DL4Proteins-notebooks
Colab Notebooks covering deep learning tools for biomolecular structure prediction and design
Peldom/papers_for_protein_design_using_DL
List of papers about Proteins Design using Deep Learning
rdk/p2rank
P2Rank: Protein-ligand binding site prediction from protein structure based on machine learning.
llnl/protlib-designer
Integer Linear Programming for Protein Library Design
samsinai/FLEXS
Fitness landscape exploration sandbox for biological sequence design.